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Hormone Therapy: We Have a Cream For That

As a woman ages, her ovaries progressively fail to produce estrogen. This failure often begins in the late 30s, and most women experience near-complete loss of production of estrogen by their mid-50s. Currently in the United States, approximately 35 million women are beyond 50 years of age. Each day some 2,500 to 3,500 additional women have their 50th birthday. The transition from normal ovarian function to ovarian failure is described as the menopausal transition. Although for many women menopause is asymptomatic and associated with little disruption of normal life and well-being, many women experience symptoms—sometimes severe and disabling—that considerably affect their quality of life. Although some women may be asymptomatic, estrogen deficiency is associated with hot flashes, sweating, insomnia, and vaginal dryness and discomfort in up to 85% of menopausal women. Hormone therapy (HT) is the most effective intervention for management of these quality-of-life symptoms. (American Association of Clinical Endocrinologists Medical Guidelines for Clinical Practice for the Diagnosis and Treatment of Menopause)

AACE Menopause Guidelines Revision Task Force