Introducing Intra-Articular Injections

Conditions like osteoarthritis happen as a result of lost articular cartilage in major joints like the knee, shoulder, and hip. Additionally, osteoarthritis can reduce certain joint properties like elasticity and viscosity of the synovial fluid (the lubricating mechanism that keeps our joints limber), which can make movement painful, or even impossible.1,2 Since the cartilage cannot regenerate or optimally heal itself, this condition is often difficult to fully treat.

However, one possible method of restoring joint health is with intra-articular injections. After two years of research and development, Innovation Compounding is introducing Lidocaine HCL 2mg/mL + Hyaluronic Acid 15mg/mL. We’ve taken the linear, unbranched polymer hyaluronic acid (for its involvement in the synovial fluid and possible anti-inflammatory action) and combined it with lidocaine hydrochloride (for its pain-relieving, anti-inflammatory properties). The final product is a gel-like solution that closely resembles the synovial fluid in the joint!

Under USP <797> sterile conditions and in our PCAB-Accredited sterile clean rooms, we’ve formulated an intra-articular injection to be used in a series of treatments for large joint conditions. Each batch produced in our pharmacy undergoes a series of potency, sterility, and endotoxin testing, assuring that the final product delivered to your doctor’s office is of the highest and most stringent quality. Much research, testing, and quality control assure that this product has been formulated to the highest standards and with the clinical research to support it.

Connect with one of our pharmacists to learn more about intra-articular injections.

Read more about what’s happening at Innovation Compounding in our spring newsletter!


  1. Marshall KW. Viscosupplementation for osteoarthritis: current status, unresolved issues and future directions. J Rheumatol. 1998;25:2056–8.
  2. George E. Intra-articular hyaluronan treatment for osteoarthritis. Ann Rheum Dis. 1998;57:637–40.

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