As-needed dosing for erectile dysfunction, while effective, can sometimes be difficult or awkward to incorporate into spontaneous sexual activity. As an alternative, low doses of tadalafil taken daily could make it possible to engage in sexual intercourse at any time, “eliminating the need to dose prior to intercourse.”1

Much research has been done comparing the outcomes of on-demand and daily doses of tadalafil. For example, in a 2005 study, 145 men were divided into two groups: the first group received 20 mg of tadalafil on demand; the second group was treated with daily doses of 10 mg tadalafil. The results of the study showed the second group reporting “better results” when compared to the first group, according to data gathered from surveys like the International Index of Erectile Dysfunction (IIEF) patient questionnaire, which asks patients to rate their sexual intercourse experience during treatment.2

While outcomes may vary from patient to patient, daily tadalafil dosing has been associated with a significantly lower rate of adverse side effects than on-demand dosing. Daily doses of tadalafil have also shown improvements in symptoms of those with benign prostatic hyperplasia (enlarged prostate), a common condition in aging men.3

At Innovation Compounding, tadalafil can be compounded to suit the needs and lifestyles of most patients. If you are dealing with ED, your doctor and our pharmacists can work together to find the best treatment option. Connect with us today to learn more!


  1. Utsav K. Bansal, Cameron Jones, Thomas W. Fuller, Charles Wessel, Stephen V. Jackman. (2018), The Efficacy of Tadalafil Daily vs on Demand in the Treatment of Erectile Dysfunction: A Systematic Review and Meta-analysis. Urology, 112: 6-11.
  2. McMahon, C. (2005), Comparison of Efficacy, Safety, and Tolerability of On‐Demand Tadalafil and Daily Dosed Tadalafil for the Treatment of Erectile Dysfunction. The Journal of Sexual Medicine, 2: 415-427. doi:1111/j.1743-6109.2005.20360.x

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