Much like menopause and andropause, somatopause refers to a transitional period (most common among older women and men) characterized by a decline, or pause, in the production of important hormones, specifically growth hormones.

Growth hormones are not only important early in life for the development of healthy bodily functions, but are also key in the regulation of those bodily functions throughout life. A decline in growth hormone production can affect one’s entire body in significant ways and is linked to a wide range of symptoms, including depression, fatigue, loss in muscle mass, and even shortened life expectancy.1

Somatopause is most commonly caused by factors associated with the normal process of aging, particularly the decreased function of the pituitary gland. This condition seems to have a greater effect on aging men, among whom, “GH secretion declines by 50% every 7 years after age 18-25 years.” 2 Other factors could potentially lead to a decrease in growth hormone production. Obesity, poor nutrition, and decreased physical fitness are strong indicators of declining growth-hormone production. Lower levels of testosterone and estrogens in men and women can also affect the secretion of growth hormones.2

For somatopause treatment, there are a variety of options available. While some therapies will attempt to replace depleted growth hormones directly, Innovation Compounding’s compounded therapies go to the root of the problem by using growth hormone-releasing peptides (GHRP-6 and GHRP-2), which reactivate natural growth hormone production in the pituitary gland, allowing the body to repair itself. We also utilize Sermorelin, a growth hormone releasing hormone or growth hormone secretagogue, which stimulates the pituitary gland to make and release growth hormone.

To learn more about GHRP, Sermorelin, somatopause, or our other hormone therapies, talk with your doctor or get in touch with one of our many qualified pharmacists.


  1. Investigación y Desarrollo. (2014, June 16). Growth hormone linked to signs of aging.ScienceDaily. Retrieved June 8, 2018 from
  2. Gentili, Angela. (2015, Dec 14). Growth Hormone Replacement in Older Men. Medscape. Retreived June 11, 2018 from

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